ILT3-Fc in Islet Transplantation ILT3-FC SUPPRESSES T CELL RESPONSES TO ALLOGENEIC HUMAN ISLET TRANSPLANTS IN HU-NOD/SCID MICE
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منابع مشابه
Immunoglobulin-Like Transcript 3-Fc Suppresses T-Cell Responses to Allogeneic Human Islet Transplants in hu-NOD/SCID Mice
OBJECTIVE The aim of our study was to explore the immunomodulatory activity of soluble immunoglobulin (Ig)-like transcript (ILT) 3-Fc in pancreatic islet transplantation and to determine its mechanism of action. RESEARCH DESIGN AND METHODS NOD/SCID mice in which diabetes was induced by streptozotocin injection were transplanted with human pancreatic islet cells. Mice in which the transplant r...
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